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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SFPQ
All Species:
9.09
Human Site:
T476
Identified Species:
20
UniProt:
P23246
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23246
NP_005057.1
707
76149
T476
M
Y
Q
K
E
R
E
T
P
P
R
F
A
Q
H
Chimpanzee
Pan troglodytes
XP_524659
619
68740
T426
M
Y
Q
K
E
R
E
T
P
P
R
F
A
Q
H
Rhesus Macaque
Macaca mulatta
XP_001088371
523
58669
M363
H
R
R
R
E
E
E
M
I
R
H
R
E
Q
E
Dog
Lupus familis
XP_532566
663
71851
M432
M
Y
Q
N
E
R
E
M
P
P
R
F
A
Q
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8VIJ6
699
75423
T468
M
Y
Q
K
E
R
E
T
P
P
R
F
A
Q
H
Rat
Rattus norvegicus
Q4KLH4
522
58741
M362
H
R
R
R
E
E
E
M
I
R
H
R
E
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513533
430
49120
M281
E
E
L
H
N
Q
E
M
Q
K
R
K
E
M
Q
Chicken
Gallus gallus
Q5ZK88
523
58452
L363
R
R
R
E
E
E
M
L
R
Q
R
E
Q
E
E
Frog
Xenopus laevis
NP_001080735
464
53169
E315
Q
D
L
M
R
R
Q
E
E
L
H
R
M
E
E
Zebra Danio
Brachydanio rerio
Q1JPY8
512
57679
Q363
D
M
I
R
H
R
E
Q
L
D
I
R
R
Q
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q04047
700
76958
I482
D
F
N
Q
E
R
S
I
G
P
R
F
A
D
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.5
45.5
84.3
N.A.
94
45.2
N.A.
59.2
45.1
40.5
42.1
N.A.
28.4
N.A.
N.A.
N.A.
Protein Similarity:
100
66.1
55.7
86.4
N.A.
95.1
56
N.A.
60.4
55.8
51
52.9
N.A.
41.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
20
80
N.A.
100
20
N.A.
13.3
13.3
6.6
20
N.A.
40
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
33.3
86.6
N.A.
100
33.3
N.A.
20
33.3
20
26.6
N.A.
53.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
46
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
19
10
0
0
0
0
0
0
0
10
0
0
0
10
0
% D
% Glu:
10
10
0
10
73
28
73
10
10
0
0
10
28
19
37
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
46
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% G
% His:
19
0
0
10
10
0
0
0
0
0
28
0
0
0
28
% H
% Ile:
0
0
10
0
0
0
0
10
19
0
10
0
0
0
0
% I
% Lys:
0
0
0
28
0
0
0
0
0
10
0
10
0
0
0
% K
% Leu:
0
0
19
0
0
0
0
10
10
10
0
0
0
0
0
% L
% Met:
37
10
0
10
0
0
10
37
0
0
0
0
10
10
0
% M
% Asn:
0
0
10
10
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
37
46
0
0
0
0
19
% P
% Gln:
10
0
37
10
0
10
10
10
10
10
0
0
10
64
10
% Q
% Arg:
10
28
28
28
10
64
0
0
10
19
64
37
10
0
0
% R
% Ser:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
28
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
37
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _